2021/07 - 至今 绍兴文理学院，生命科学学院，教授。
2017/07-2021/07 兰州大学，生命科学学院，副教授。
2012/07-2014/08 浙江师范大学，生命科学学院，研究助理。

本科生：
《植物生理学》

研究生：
《高级分子生物学》

研究方向
植物网格蛋白介导的内吞的机制研究
植物网格蛋白介导的内吞的功能研究

细胞是生命的基本单位。生命是如何蕴藏在细胞里的，细胞是如何承载生命的，目前都不得而知。早在1925年，生物学大师威尔逊就提出：“一切生命的关键问题都要到细胞中去寻找答案”。细胞的深入研究是揭开生命奥秘、改造生命和征服疾病的关键。因此，细胞生物学已经成为现代生命科学的基石之一。植物细胞生物学领域有着丰富的发现历史，最早可以追溯到罗伯特·胡克发现细胞的时代。显微镜技术的发展使得亚细胞结构的可视化成为可能，生物化学、遗传学和分子生物学的应用使得调控关键细胞过程的机制得以揭示。

囊泡运输(Vesicle Trafficking)是当前细胞生物学研究领域中的重要热点之一，是理解细胞信号传导的关键所在。诺贝尔生理学或医学奖已经先后四次授予从事该研究领域的科学家。网格蛋白介导的内吞CME (Clathrin-Mediated Endocytosis)是囊泡运输的最关键过程之一，直接调控胞外物质吸收、质膜蛋白丰度和胞内外信号传递等重要细胞生物学过程。然而，人们对植物细胞CME的生物学功能及其调控机制知之甚少。课题组专注于植物CME的机制和功能研究，在植物CME研究领域已取得一系列阶段性成果。在国内外学术刊物上共发表31篇学术论文，其中在Nature Plants、Plant Cell、Molecular Plant、New Phytologist、Journal of Integrative Plant Biology和Plant Physiology等国际植物学主流刊物上发表20篇SCI论文，1篇被ESI选为“高被引论文”。任多家SCI刊物审稿人，参与承办第十八届“全国植物基因组学大会”。

主持或参与国家自然科学基金7项。

代表性论著：

1.第一作者（含共一）或通讯作者（含共通）

(1) Wang YT, Yan X, Xu M, Qi WY, Shi CJ, Li XH, Ma JQ, Tan D, Shou JX, Wu HJ, Pan JW, Li B*, and Wang C*. TMK1-mediated auxin signal regulates membrane-associated clathrin in Arabidopsis roots. Journal of Integrative Plant Biology, 2023, 65(1):82-99.

(2) Liu C, Li Z, Tian D, Xu M, Pan J, Wu H*, Wang C* and Oteguic M*. AP1/2β-Mediated Exocytosis of Tapetum-specific transporters is required for pollen development in Arabidopsis thaliana. Plant Cell, 2022, 34(10):3961-3982.

(3) Xu M, Yan X, Liu C, Tian D, Yang Q, Pan JW, Wang C*. Adaptor protein complex 1-mediated post-Golgi trafficking of RPG1 is critical for pollen wall development and microspore Cell integrity in Arabidopsis. New Phytologist, 2022, 235(2):472-487.

(4) Hu TW, Yin SP, Sun J, Linghu YT, Ma JQ, Pan JW, Wang C*. Clathrin light chains regulate hypocotyl elongation through polarization of the auxin transporter PIN3 in Arabidopsis. Journal of Integrative Plant Biology, 2021, 63(11):1922-1936.

(5) Yang CH#, Wang C#, Singh S, Fan N, Liu S, Zhao L, Cao HL, Yang CW* and Huang CF*. Golgi-localized manganese transporter PML3 regulates Arabidopsis growth through modulating Golgi glycosylation and cell wall biosynthesis. New Phytologist, 2021, 231(6):2200-2214.

(6) Ni M#, Zhang L#, Shi Y#, Wang C#, Lu Y, Pan J, Liu J*. Excessive cellular S-nitrosothiol impairs endocytosis of auxin efflux transporter PIN2. Frontiers in Plant Science, 2017, 8:1988.

(7) Wang C, Yan X, Pan J*. Immunofluorescence analysis of membrane-associated proteins for clathrin-mediated endocytosis in plant root cells. Methods in Molecular Biology, 2017, 1662:151-157.

(8) Wang C, Xu W, Jin H, Zhang T, Lai J, Zhou X, Zhang S, Liu S, Duan X, Wang H, Peng C, Yang C*. A putative chloroplast-localized Ca2+/H+ antiporter CCHA1 is involved in calci-um and pH homeostasis and required for PSII function in Arabidopsis. Molecular Plant, 2016, 9(8):1183-1196.

(9) Wang C#, Hu T#, Yan X#, Meng T, Wang Y, Wang Q, Zhang X, Gu Y, Sánchez-Rodríguez C, Gadeyne A, Lin J, Persson S, Van Damme D, Li C, Bednarek SY, Pan J*. Differential regulation of clathrin and its adaptor proteins during membrane recruitment for endocytosis. Plant Physiology, 2016, 171(1):215-229.

(10) Wang C, Yan X, Chen Q, Jiang N, Fu W, Ma B, Liu J, Li C, Bednarik SY, Pan J*. Clathrin light chains regulate clathrin-mediated trafficking, auxin signaling, and development in Arabidopsis. Plant Cell, 2013, 25(2):499-516.


2.合作

(1) Qin X, Zhang X, Ma C, Yang X, Hu Y, Liu Y, Hu Y, Wang D, lv X, Wang C, Shou J*, Li B*. Rice OsCIPK17-OsCBL2/3 module enhances shoot Na+ exclusion and plant salt tolerance in transgenic Arabidopsis. Plant Physiology and Biochemistry, 2024, https://doi.org/10.1016/j.plaphy.2024.109034

(2) Zhou J, Ma J, Yang C, Zhu X, Li J, Zheng X, Li X, Chen S, Feng L, Wang P, Man Ip Ho, Ma W, Liao J, Li F, Wang C, Zhuang X, Jiang L, Kang B*, Gao C*. A non-canonical role of ATG8 in the Golgi recovery from heat stress in plants. Nature Plants, 2023, 9(5):749-765.

(3) Wang CJ, Ou DW, Wang C, Lu X, Du JJ, Li JQ, Lai JB, Zhang SC, Yang CW*. Functional characterization of a chloroplast-localized Mn2+(Ca2+)/H+ antiporter, ZmmCCHA1 from Zea mays ssp. mexicana L. Plant Physiology and Biochemistry, 2020, 6;155:396-405.

(4) Huang RH, Shu S, Liu ML, Wang C, Jiang B, Yang CW, Zhang SC*. Nuclear PROHIB-ITIN3 maintains genome integrity and cell proliferation in root meristem through MINI-CHROMOSOME MAINTENANCE 2. Plant Physiology, 2019, 179(4): 1669-1691.

(5) Reynolds GD, Wang C, Pan J, Bednarek SY*. Inroads into internalization: five years of endocytic exploration. Plant Physiology, 2018, 176(1):208-218.

(6) Mayers JR, Hu T, Wang C, Tan Y, Pan J, Bednarek SY*. SCD1 and SCD2 form a complex that functions with the Exocyst and RabE1 in exocytosis and cytokinesis. Plant Cell, 2017, 29(10):2610-2625.

(7) Lu X, Yang L, Yu M, Lai J, Wang C, McNeil D, Zhou M*, Yang C*. A novel Zea mays ssp. mexicana L. MYC-type ICE-like transcription factor gene ZmmICE1, enhances freez-ing tolerance in transgenic Arabidopsis thaliana. Plant Physiology and Biochemistry, 2017, 113:78-88.

(8) Zhang Y#, Yu Q#, Jiang N#, Yan X, Wang C, Wang Q, Liu J, Zhu M, Bednarek SY, Xu J, Pan J*. Clathrin regulates blue light-triggered lateral auxin distribution and hypocotyl phototropism in Arabidopsis. Plant Cell & Environment, 2017, 40(1):165-176.

(9) Yu Q, Zhang Y, Wang J, Yan X, Wang C, Xu J, Pan J*. Clathrin-mediated auxin efflux and maxima regulate hypocotyl hook formation and light-stimulated hook opening in Arabidopsis. Molecular Plant, 2016, 9(1):101-112.

(10) Shi YF#, Wang DL#, Wang C, Culler AH, Kreiser MA, Suresh J, Cohen JD, Pan J, Baker B, Liu JZ*. Loss of GSNOR1 function leads to compromised auxin signaling and polar auxin transport. Molecular Plant, 2015, 8(9):1350-1365.

(11) McMichael CM, Reynolds GD, Koch LM, Wang C, Jiang N, Nadeau J, Sack FD, Gelderman MB, Pan J, Bednarek SY*. Mediation of clathrin-dependent trafficking during cyto-kinesis and cell expansion by Arabidopsis stomatal cytokinesis defective proteins. Plant Cell, 2013, 25(10):3910-3925.